The laboratory of Professor Volker Haase studies hypoxia response pathways in erythropoiesis and iron metabolism, chronic kidney injury and ischemic pre-conditioning, inflammation, kidney development and tumorigenesis. A major focus of the lab is on the interplay between hypoxia signaling, metabolism and cellular differentiation and its regulation by the prolyl hydroxylase domain (PHD) / hypoxia-inducible factor (HIF) / von Hippel-Lindau tumor suppressor (VHL) signaling axis. Haase group members take advantage of powerful cutting-edge mouse genetics, biochemical, metabolomic and single cell approaches to study oxygen and mitochondrial metabolism in kidney, urologic and other diseases. Click on links for information about career opportunities in the Haase lab and publications.
Lab News and Updates
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Anemia of CKD
HIF-PHIs in kidney transplant patients
April 2024
Hypoxia-Inducible Factor Stabilizers: An Evolving Role in Post-Transplant Anemia