Book Chapters and Media Files

Changes in tissue oxygen levels occur under pathological conditions and physiologically during development. The laboratory of Professor Volker H. Haase studies hypoxia response pathways and their therapeutic applications in erythropoiesis and iron metabolism, chronic kidney injury and ischemic pre-conditioning, inflammation, kidney development and tumorigenesis.

A major focus of the lab is on the interplay between hypoxic signaling, metabolism and cellular differentiation and its regulation by the prolyl hydroxylase domain (PHD) / hypoxia-inducible factor (HIF) / von Hippel-Lindau tumor suppressor (VHL) signaling axis. Haase group members take advantage of powerful cutting-edge mouse genetics, biochemical, metabolomic and single cell approaches to study oxygen and mitochondrial metabolism in kidney, urologic and other diseases. Click on links for information about career opportunities in the Haase lab and recent publications.

Book Chapters

Media Library

HIF stabilizers in renal anemia

VuMedi Webinar: Therapeutic options for anemia in chronic kidney disease, 03/28/18
(click on image to view video)
Slide Set: HIF stabilizers
(click on image to download slide set)


AJKD Blog NephMadness 2021:
HIF-PHIs in anemia of CKD
(link to AJKD blog)

Renal and Urology News Blog 2019:
HIF Activators in Renal Anemia
(link to RUN news blog)

Discoveries in Medicine Blog 2019:
Therapeutic Targeting of the PHD/HIF Pathway: New Approaches to Renal Anemia
(link to news blog)

AJKD Blog 2016:
Vadadustat and Anemia
(link to AJKD blog)

Nature Biotechnology article, 2013:
New anaemia drugs
(link to article)