Volker Haase Lab

Principal Investigator

Volker H. Haase, M.D., Dr. med.
The Krick-Brooks Chair in Nephrology
Professor of Medicine and Professor of Molecular Physiology and Biophysics at Vanderbilt University

Volker Haase is a physician-scientist with clinical training in Internal Medicine and Nephrology and holds the Krick-Brooks Chair in Nephrology at Vanderbilt University. He is a leader in the field of mammalian oxygen sensing, prolyl hydroxylase domain oxygen sensor and HIF biology, and trained in experimental biology and genome editing under Professor Rudolf Jaenisch at the Whitehead Institute. Professor Haase is an alumnus of the Studienstiftung des Deutschen Volkes, the recipient of the 2006 Sir William Osler Young Investigator award. He is a member of the American Society for Clinical Investigation (ASCI) and was elected to the Association of American Physicians (AAP) in 2016. As of 2018 Professor Haase serves the NIH as a standing member of the Pathobiology of Kidney Disease (PBKD) study section. In addition to directing his research group, Professor Haase provides inpatient care in General Internal Medicine and Nephrology (see Clinical Activities in Internal Medicine and Nephrology).

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Mikhail Burmakin, M.D., Ph.D.

Researcher

Mikhail Burmakin trained in Pediatric Nephrology and Molecular Biology.  Mikhail is interested in the effects of HIF prolyl hydroxylase domain enzyme inhibition on renal physiology and works with Volker Haase on single cell transcriptomic profiling for the study of kidney disease.

Douglas B. Clayton, M.D.

Assistant Professor of Surgery

Doug Clayton is an Assistant Professor of Urologic Surgery and is a Pediatric Urologist. He is pursuing a career as a clinician scientist funded through a K08 Mentored Clinical Scientist Award. Doug’s research focus is on understanding hypoxia responses in bladder inflammation. When not seeing patients or working in the lab, Doug enjoys spending time with his wife and two young sons.

Olena Davidoff, M.S.

Lab Manager

Olena Davidoff received a Masters Degree in Molecular Diagnostics from Odessa University. Olena is interested in mouse genetics and animal work.

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Nan Guan, M.D.

Visiting Graduate Student

Nan Guan received her M.D. degree (Bachelor of Medicine) from Fudan University in Shanghai, China.  She is the recipient of a China Scholarship Council fellowship and has joined the Haase laboratory to work on HIF and mitochondrial signaling in kidney disease as part of her Ph.D. studies.

Hanako Kobayashi, Ph.D.

Research Assistant Professor of Medicine

Hanako Kobayashi received her Ph.D. in Molecular Nutrition Science from the University of California, Berkeley. Hanako studies the regulation of EPO in the kidney and is interested in the role of prolyl hydroxylase domain enzymes and HIF in the pathogenesis of acute and chronic kidney injury.

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Belinda Li, M.D.

Fellow in Pediatric Urology

Belinda Li received her M.D. from the State University of New York (SUNY) Downstate College of Medicine. She completed her Urology residency at Loyola University in Chicago, IL and is a currently a fellow in Pediatric Urology. Belinda is interested in hypoxic signaling in bladder injury and inflammation.

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Carmen Tong, D.O.

Fellow in Pediatric Urology

Carmen Tong received her D.O. from the Arizona College of Osteopathic Medicine in Glendale, Arizona.  Carmen studies the role of mitochondria in polycystic kidney disease and diseases of the bladder.  She also manages the Haase lab social media account @HIFpathway.

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Kyoji Yamaguchi, Ph.D.

Research Assistant Professor of Medicine

Kyoji Yamaguchi received his Ph.D. in Agricultural Sciences (Applied Microbiology) from Nagoya University in Japan after conducting research on protein secretion and localization signals under Prof. Masayori Inouye, which was published in Cell.  After spending a large part of his career as a Chief Scientist in pharmaceutical industry in Japan, where he led drug development programs in the HIF domain, he has now transitioned back to academia and joined the Vanderbilt faculty. His interests are in oxygen sensing in renal anemia and kidney injury.

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